One of the major mechanisms responsible for multidrug resistance in cancer chemotherapy is overexpression of some members of the ATP-binding cassette (ABC) transporter superfamily, including ABCB1, ABCC1 and ABCG2, resulting in decreased intracellular levels of drugs [reviewed in (58)]

By joshbutnerforcongress

One of the major mechanisms responsible for multidrug resistance in cancer chemotherapy is overexpression of some members of the ATP-binding cassette (ABC) transporter superfamily, including ABCB1, ABCC1 and ABCG2, resulting in decreased intracellular levels of…

Furthermore, Tat-mediated manifestation of ICAM-1 played an essential part in monocyte adhesion, resulting in increased recruitment of inflammatory cells onto the vessel endothelium

By joshbutnerforcongress

Furthermore, Tat-mediated manifestation of ICAM-1 played an essential part in monocyte adhesion, resulting in increased recruitment of inflammatory cells onto the vessel endothelium. from the respective miRNAs with anti-miR oligonucleotides led to induction of ICAM-1…

Phylogenet

By joshbutnerforcongress

Phylogenet. from other CoV Mpros, the HCoV-HKU1 Mpro structure reported here provides insights into both substrate preference and the design of antivirals targeting CoVs. Coronaviruses (CoVs) are positive-strand RNA viruses that have been identified as…

Furthermore, it demonstrates dynamic ubiquitylation, deubiquitylation and proteasomal turnover are essential for the efficient clearance of two prototypic types of SGs, that’s, SGs induced by temperature and arsenite surprise

By joshbutnerforcongress

Furthermore, it demonstrates dynamic ubiquitylation, deubiquitylation and proteasomal turnover are essential for the efficient clearance of two prototypic types of SGs, that’s, SGs induced by temperature and arsenite surprise. Although generally there is considerable evidence…

(PDF 105 kb) 12906_2019_2439_MOESM3_ESM

By joshbutnerforcongress

(PDF 105 kb) 12906_2019_2439_MOESM3_ESM.pdf (106K) GUID:?98CD0C82-D821-4E15-8CA9-8EDC3BA31D45 Additional file 4: Shape S1. 27 kb) 12906_2019_2439_MOESM5_ESM.pdf (27K) GUID:?A31EE651-34A5-4A0D-84E8-AC8D6036AA2F Extra document 6: Shape S3. Dextromethorphan Eslicarbazepine Acetate in vitro inhibition information of CYP2D6 by research inhibitor: Quinidine (0.1-1-2-5-10-100…