* p 0
* p 0.05, **p 0.01 and ***p 0.001. To verify the reversal of level of resistance to Hsp90 inhibitor simply by SIRT1 inhibitor in additional tumor stem-like cells, we used Compact disc44+ HCT-15 cells with high colony forming activity and Compact disc44- HCT-15 cells with poor colony forming activity separated from human being cancer of…