However, complement, and especially C5a, can contribute to organ damage in concert with the cytokine storm in the later stages of sepsis79,144
However, complement, and especially C5a, can contribute to organ damage in concert with the cytokine storm in the later stages of sepsis79,144. C3 convertase complexes (species) or parasites, formation of TCC and subsequent cell lysis (Fig. 1b). Given its central and early role in antimicrobial attack and the millennia of co-evolution between microorganisms and this…