Five days after injury, the average CSA of muscle fibers was significantly decreased inPax7-CreER:Islrfl/flmice compared to theIslrfl/flmice (Fig
Five days after injury, the average CSA of muscle fibers was significantly decreased inPax7-CreER:Islrfl/flmice compared to theIslrfl/flmice (Fig.5e). as an important regulator for skeletal muscle regeneration. Satellite cells are crucial for skeletal muscle regeneration. Here the authors show that immunoglobulin superfamily containing leucine-rich repeat (Islr) promotes skeletal muscle regeneration via a mechanism involving Dishevelled-2 stabilization…