7and and and and < 0
7and and and and < 0.05; **< 0.01. Discussion Our findings indicate that macrophage PPAR and RXR are required for the efficient disposal of apoptotic bodies, which prevents the release of intracellular components and the consequent loss of SB 334867 immunological self-tolerance, and might explain the development of an SLE-like nephritis in mice lacking macrophage…